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Ceftazidime (Tazicef, Fortaz)

A cephalosporin antibiotic given by injection or IV infusion in a clinic or hospital for serious bacterial infections, including lung, skin, urinary, and bloodstream infections.

Plan year 2027 · Source: CMS · Checked 2026-10-31

How Medicare covers it

Usual path Part B (injections and infusions given by a clinician — J0713, see the Part B basis in this package). The Part D aggregation in this package is carried exactly as computed. Part A during a covered inpatient stay.

Coverage details
Part B statusCMS Part B Spending by Drug HCPCS file (RY26, data through 2024) carries J0713 (ceftazidime): the clinician-administered path is Part B. The ceftazidime/avibactam combination (Avycaz, J0714) is a different product and is explicitly NOT matched.
Medicare AdvantageMost Medicare Advantage plans that include drug coverage (MAPD plans) use the same formulary-and-tier system; the plan's own drug list decides coverage and copay — check the plan's formulary.
Medicare Supplement (Medigap)Medicare Supplement (Medigap) plans sold today do not include prescription drug coverage; drug coverage comes from Part D or an MAPD plan.

What it treats

Ceftazidime (Tazicef) treats serious bacterial infections caused by susceptible bacteria, including lower respiratory tract infections and pneumonia, skin and skin-structure infections, urinary tract infections, bacterial septicemia (blood infection), bone and joint infections, gynecologic infections, intra-abdominal infections, and central nervous system infections including meningitis. It does not treat viral infections such as colds or flu.

What it is for, in depth

Ceftazidime, sold as Tazicef and Fortaz, is a cephalosporin antibiotic used to treat serious bacterial infections caused by susceptible bacteria. The label lists lower respiratory tract infections and pneumonia, skin and skin-structure infections, urinary tract infections, bacterial septicemia, which is a blood infection, bone and joint infections, gynecologic infections, intra-abdominal infections, and central nervous system infections including meningitis. It does not treat viral infections such as colds or flu. It is typically prescribed for patients in a clinic or hospital whose infection is serious enough to need an injected antibiotic, with the dose and length of treatment set by the type of infection and by kidney function. It is given as a powder in a vial that is mixed and given by a healthcare professional into a vein or into a muscle. Matched forms include ceftazidime 1000 MG injection, ceftazidime 2000 MG injection, and ceftazidime 200 MG/ML injectable solution, including Tazicef-named forms.

How it works

Ceftazidime is a broad-spectrum beta-lactam (cephalosporin) antibacterial. It kills bacteria by blocking the building of the bacterial cell wall.

How it is taken

It is a powder in a vial that is mixed and given by a healthcare professional into a vein (intravenously) or into a muscle (intramuscularly). The usual adult dose is 1 gram every 8 to 12 hours; the dose and schedule depend on the infection and on kidney function, and the dose is lowered in people with kidney problems.

Common side effects

The most common effects were local reactions after IV injection (pain, phlebitis, and inflammation at the injection site, in fewer than 2% of patients), allergic reactions such as itching, rash, and fever (2%), and stomach and bowel symptoms such as diarrhea, nausea, vomiting, and abdominal pain (fewer than 2%). Headache, dizziness, and tingling were reported in fewer than 1%.

Serious warnings

Serious allergic reactions, including anaphylaxis, can occur, especially in people allergic to cephalosporins or penicillins — cross-allergy occurs in up to 10% of people with a penicillin allergy history. Clostridioides difficile diarrhea (CDAD), ranging from mild diarrhea to fatal colitis, has been reported and can occur over two months after treatment. High blood levels in people with kidney problems can cause seizures, encephalopathy (confusion and reduced alertness), coma, muscle twitching, and myoclonia, so the dose must be reduced when the kidneys do not work well.

Who should be careful

People who have had an allergic reaction to ceftazidime or any cephalosporin must not take it. People with a penicillin allergy, kidney impairment (dose reduction is needed, and older patients are more likely to have reduced kidney function), or a history of stomach or bowel disease, especially colitis, need extra care. It should be used during pregnancy only if clearly needed, and caution is advised for nursing mothers because small amounts pass into breast milk.

Major interactions

Using cephalosporins together with aminoglycoside antibiotics or strong water pills such as furosemide has been reported to harm the kidneys, so kidney function should be watched. Chloramphenicol can oppose the bacteria-killing effect of ceftazidime and that combination should be avoided. Ceftazidime can cause a false-positive urine glucose result with CLINITEST tablets, Benedict's solution, or Fehling's solution.

Why it is in its tier

Most listing plans place ceftazidime on Tier 4. It is listed by 100.0% of Part D plans, and 76.4% of those listing plans use Tier 4, so this is a clear majority placement with full listing breadth. Tier 4 is a non-preferred tier, which usually means a higher coinsurance share rather than a small flat copay, so patients often pay more than they would on a lower tier. The data-visible drivers fit that placement: this is a hospital and clinic injected antibiotic for serious infections, in generic and Tazicef-named injection and solution forms, rather than a routine home tablet, even though listing is universal. The CMS dashboard average spending was $301.72 per beneficiary. That dashboard figure is a CMS program average, not a copay, and individual plans vary in what a patient actually pays.

What official patient guides say

Ceftazidime injection comes as a powder to be mixed with liquid and given intravenously (into a vein) or intramuscularly (into a muscle), every 8 or 12 hours; your doctor will decide how long you need treatment. You may receive it in a hospital or administer it at home — if you will be receiving it at home, your healthcare provider will show you how to use the medication, and you should be sure you understand those directions and ask if you have any questions. Use ceftazidime injection until you finish the prescription, even if you feel better; stopping too soon or skipping doses may leave the infection incompletely treated. If you miss a dose, use it as soon as you remember, unless it is almost time for the next dose — then skip the missed dose and continue your regular schedule; do not use a double dose. Your healthcare provider will tell you how to store your medication — store it only as directed and make sure you understand how to store it properly. Dispose of unneeded medication through a medicine take-back program; do not flush it.

Source: MedlinePlus — Ceftazidime Injection

Part D formulary coverage

Formulary summary
Most common tier4
Plans listing this drug5495
Total Part D plans5495
Share of plans listing it100
Formularies listing it286
TierPlans
Tier 1131 plans
Tier 2768 plans
Tier 3388 plans
Tier 44198 plans
Tier 610 plans

Source: CMS Prescription Drug Plan Formulary, Pharmacy Network, and Pricing Information Files — Monthly file 2026-10-15 (plan year 2027), file 2027_20261008.zip (data.cms.gov dataset ed1496ea-23e7-41f1-9292-172fa842ccfb): basic drugs formulary file + plan information file, both dated 20261031 inside the zip; downloaded and aggregated 2026-10-30. Medication RxCUI sets resolved through the NLM RxNav (RxNorm) API.

What you pay

With Medicare Part D
Most common tierTier 4
Typical copay$95 — half of plans charge between $40 and $100
Typical coinsurance27.0% of the price
Based on4135 plans that cover this drug · 2027 plan year

Without insurance, the cash benchmark is $3.7045 per unit (CEFTAZIDIME 1 GM VIAL) — about $111.13 for 30 units. NADAC benchmark — the average price pharmacies pay (CMS, as of 2026-11-04). Pharmacy shelf prices vary.

A tier is not a price; what you pay depends on your plan, pharmacy, and benefit stage; Extra Help or Medicaid can lower it further.

Sources: CMS Plan Benefit Package + formulary data; CMS NADAC · Checked 2026-11-07

Part D spending averages (2024)

Brand nameGeneric nameTotal claims 2024Total spending 2024Total beneficiaries 2024Rank by beneficiaries 2024
CeftazidimeCeftazidime157041.71013e+0656681161
Tazicef*Ceftazidime64633229.92072454

Source: CMS Medicare Part D Spending by Drug (Drug Spending Dashboard), release RY26 P04 V10, data through 2024 (DSD_PTD_RY26_P04_V10_DY24_BGM.csv), downloaded 2026-10-30

Companies covering this drug

5,495 plans from 509 companies list this drug on a formulary for 2027. Search by company or plan name, or filter by tier. Cost sharing is the plan's published amount for this drug's tier in the initial coverage stage (1-month retail supply), where the plan publishes it; a blank means the plan does not publish it.

CompanyPlanTierCopayCoinsurance

A tier is not a price; what you pay depends on your plan, pharmacy, and benefit stage; Extra Help or Medicaid can lower it further.

Coverage and costs change. Drug lists (formularies), tiers, and copays can change during the year and differ by plan. Always check with your insurance company or plan directly to confirm what is covered and what you will pay.

Care and Living Guide is not connected with or endorsed by the U.S. government or the federal Medicare program. For official information visit Medicare.gov or call 1-800-MEDICARE.

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